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John V. Frangioni, M.D., Ph.D. Associate Professor of Medicine and Associate Professor of Radiology |
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Dr. Frangioni is an internationally renowned expert in molecular imaging. His laboratory focuses on the development of novel medical devices and disease-specific contrast agents for diagnosing and treating cancer. Dr. Frangioni is inventor of the FLARE™ and mini-FLARE™ intraoperative near-infrared fluorescence imaging systems, which use invisible light to find tumors, blood vessels, and nerves during surgery. His laboratory has also developed numerous cancer- and disease-specific contrast agents for use with FLARE™. The FLARE™ and mini-FLARE™ systems are currently being used in clinical trials for breast cancer sentinel lymph node mapping, lung cancer sentinel lymph node mapping, and breast cancer reconstructive surgery.
Dr. Frangioni has been the Principal Investigator of twelve peer-reviewed research grants from the National Institutes of Health totaling over $25M dollars. He has published over 90 peer-reviewed publications and is committed to sharing the results of his NIH-funded research with other academic investigators. A data sharing repository can be found on his website (frangionilab.org). His research has been featured in the Boston Globe, Popular Science, ABC News Science Central, Canadian Public Radio, and Bavarian Public Television.
Dr. Frangioni is an invited reviewer for numerous international foundations and 27 high-impact peer-reviewed journals and is also on the Editorial Board of Molecular Imaging. He is a frequent invited speaker or keynote speaker at national and international meetings and is also a dedicated teacher, having trained over 45 post-doctoral fellows, visiting professors, research associates, and students.
Dr. Frangioni is the recipient of several awards including Mentor of the Year at Harvard Medical School and the Edward M. Kennedy Award for Healthcare Innovation, and he has been inducted into the American Society for Clinical Investigation. He is also a Visiting Professor of the Royal Netherlands Academy of Arts and Sciences at the Leiden University Medical Center.
Dr. Frangioni received his undergraduate degree in Engineering Sciences from Harvard College. He received his M.D. from Harvard Medical School and the Massachusetts Institute of Technology’s Health Science and Technology (HST) Program, and his Ph.D. in Cellular and Molecular Physiology from Harvard Graduate School of Arts and Sciences. He completed an internal medicine residency at Brigham and Women’s Hospital and a medical oncology fellowship at Beth Israel Deaconess Medical Center. He has been board certified in internal medicine and medical oncology, and is an Attending Physician in the Division of Hematology/Oncology at the Beth Israel Deaconess Medical Center.
