Society for Molecular Imaging cover image

Humblet V, Lapidus R, Williams LR, Tsukamoto T, Rojas C, Majer P, Hin B, Ohnishi S, De Grand AM, Zaheer A, Renze JT, Nakayama A, Slusher BS, Frangioni JV. High affinity near-infrared fluorescent small molecule contrast agents for in vivo imaging of prostate-specific membrane antigen. Mol Imaging

Molecular Imaging
October-December 2005
Volume 4, Number 4

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Nakayama A, del Monte F, Hajjar RJ, Frangioni JV. Functional near-infrared fluorescence imaging for cardiac surgery and targeted gene therapy. Mol Imaging .

Molecular Imaging
October 2002
Voume 1, Number 4

Society for Molecular Imaging cover image

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Journal of Cell Science image

Frangioni JV, Moghal N, Stuart-Tilley A, Neel BG, Alper SL. The DNA binding domain of retinoic acid receptor - is required for ligand-dependent suppression of proliferation: Application of general purpose mammalian coexpression vectors. J Cell Science 1994;

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Image of histologic analysis of frozen sections of SLN

Histologic analysis of frozen sections of the SLN.

Kim S, Lim YT, Soltesz EG, De Grand AM, Lee J, Nakayama A, Parker JA, Mihaljevic T, Laurence RG, Dor DM and others. Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping. Nat Biotechnol. .

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Images of esophagus of pig using color video

In vivo esophagus of pig visualized with color video (left),
NIR fluorescence (middle), and color-NIR merge images (right).

Parungo CP, Ohnishi S, Kim SW, Kim S, Laurence RG, Soltesz EG, Chen FY, Colson YL, Cohn LH, Bawendi MG and otders. Intraoperative identification of esophageal sentinel lymph nodes with near-infrared fluorescence imaging. J Thorac Cardiovasc Surg. .

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In vivo image of lymph node group in the pig

In vivo imaging of the highest superior mediastinal lymph node group in the pig. QDs
injected into the right pleural space drain to and remain in the ipsilateral highest
superior mediastinal lymph node (arrow), as imaged with color video (left), NIR
fluorescence (middle), and color-NIR merge (right).

Parungo CP, Colson YL, Kim SW, Kim S, Cohn LH, Bawendi MG, Frangioni JV. Sentinel lymph node mapping of the pleural space. Chest. .

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Autofluorescence of vital organs and bodily fluids of mouse

Wavelength-dependent autofluorescence of vital organs and bodily fluids of a hairless,
athymic nu/nu mouse. Arrows mark the location of the gallbladder (GB), small
intestine (SI), and bladder (Bl).

Frangioni JV. In vivo near-infrared fluorescence imaging. Curr Opin Chem Biol. .

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Endogenous and ectopic wild-type human PSMA

NIR fluorescence imaging of endogenous and ectopic wild-type human PSMA on living cells
and the contribution of endocytosis to signal strength. PSMA-negative PC-3 cells infected 48 hours previously with an adenovirus co-expressing GFP and either wild-type PSMA or Erb-B2.

Humblet V, Lapidus R, Williams LR, Tsukamoto T, Rojas C, Majer P, Hin B, Ohnishi S, De Grand AM, Zaheer A, Renze JT, Nakayama A, Slusher BS, Frangioni JV. High affinity near-infrared fluorescent small molecule contrast agents for in vivo imaging of prostate-specific membrane antigen. Mol Imaging

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Intraoperative NIR fluorescence imaging system overview

Intraoperative NIR fluorescence imaging system overview.

Gioux S, De Grand AM, Lee DS, Yazdanfarc S, Idoine JD, Lomnes SJ, Frangioni JV. Improved optical sub-systems for intraoperative near-infrared fluorescence imaging. In: Analoui M, Dunn DA, editors. Proceedings of SPIE (International Society for Optical Imaging). Optical Methods in Drug Discovery and Development Volume 6009; 2005; Oct 23-26; Boston, MA. Bellingham, WA; 2005. p.39-48.

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To view the movies, you will need QuickTime viewer. Click on the link for download information.

Swine colon SLN mapping NIR QDs

Swine Colon SLN Mapping NIR QDs

  • Soltesz EG, Kim S, Kim SW, Laurence RG, De Grand AM, Parungo CP, Cohn LH, Bawendi MG, Frangioni JV. Sentinel lymph node mapping of the gastrointestinal tract by using invisible light. Ann Surg Oncol. .
 
Swine distal foot SLN mapping HSA 800 Swine distal foot SLN mapping HSA800

Swine Distal Foot SLN Mapping HSA800

  • Ohnishi S, Lomnes SJ, Laurence RG, Gogbashian A, Mariani G, Frangioni JV. Organic alternatives to quantum dots for intraoperative near-infrared fluorescent sentinel lymph node mapping. Mol Imaging. .
  • Gioux S, De Grand AM, Lee DS, Yazdanfarc S, Idoine JD, Lomnes SJ, Frangioni JV. Improved optical sub-systems for intraoperative near-infrared fluorescence imaging. In: Analoui M, Dunn DA, editors. Proceedings of SPIE (International Society for Optical Imaging). Optical Methods in Drug Discovery and Development Volume 6009; 2005; Oct 23-26; Boston, MA. Bellingham, WA; 2005. p.39-48.
 
Swine lung RUL SLN mapping NIR

Swine Lung RUL SLN Mapping NIR QDs

  • Soltesz EG, Kim S, Laurence RG, DeGrand AM, Parungo CP, Dor DM, Cohn LH, Bawendi MG, Frangioni JV, Mihaljevic T. Intraoperative sentinel lymph node mapping of the lung using near-infrared fluorescent quantum dots. Ann Thorac Surg. ; discussion 269-77.
 
Swine skin SLN mapping HSA800

Swine Skin SLN Mapping HSA800

  • Ohnishi S, Lomnes SJ, Laurence RG, Gogbashian A, Mariani G, Frangioni JV. Organic alternatives to quantum dots for intraoperative near-infrared fluorescent sentinel lymph node mapping. Mol Imaging. .

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image of a molecule
 
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